Andrea Henle

  • Associate Professor of Biology
    Email Address:
    ahenle@carthage.edu
    Office location:
    Straz Center 294
    Phone
    262-551-6315

    Professor Andrea Henle earned a B.A. in biochemistry from the College of St. Benedict and a Ph.D. in biomedical sciences-immunology from the Mayo Clinic.

    Prof. Henle joined the Carthage faculty in fall 2015 after a year as a visiting professor at Bard College. She previously completed a postdoctoral research and teaching fellowship at Massachusetts Institute of Technology and taught courses in biology at MIT, Harvard University, Carleton College, and in Singapore.

    Her research focuses on the intersection of cell biology, cancer, and immunology. She uses both the zebrafish model organism and cancer cell lines to model melanoma and understand the cellular events that lead to cancer initiation and progression. She is particularly interested in discovering ways to get the immune system to recognize and fight tumors.

    She has authored publications in journals such as Pigment Cell and Melanoma Research, The Journal of Immunology, and the Journal of Visualized Experiments, and is a co-inventor on a patent for a peptide that is being explored as a possible vaccine to prevent breast cancer recurrence.

    Media Mentions:

     Looking back and ahead to NASA’s new goal of returning to the moon by 2024 
    Professor Henle writes her thoughts on the 50th anniversary of the moon landing and NASA’s goal to return to the moon. (Kenosha News, July 21, 2019)

    Spotlight on early-career researchers: an interview with Andrea Henle 
    Professor Henle was recently interviewed for a spotlight on early-career researchers. (Nature International Journal of Science, February 7, 2019)

    • Ph.D. — Biomedical Sciences-Immunology, Mayo Graduate School, Mayo Clinic
    • Postdoctoral Research and Teaching Fellowship, Cancer Biology, Massachusetts Institute of Technology
    •  B.A. — Biochemistry, College of St. Benedict
    • BIO 1110 Molecules, Cells, and Organisms
    • BIO 2300 Cell and Molecular Biology
    • BIO 4300 Immunology
    • BIO 4900 Research in Biology
    • BIO 400 Space Biology — Human Health and Disease from Space to Earth
    • BIO 200 Cancer — Historical and Modern Perspectives

    Professor Henle’s research focuses on the intersection of cell biology, cancer, and immunology. She uses both the zebrafish model organism and cancer cell lines to model melanoma, and understand the cellular events that lead to cancer initiation and progression. She is particularly interested in discovering ways to get the immune system to recognize and fight tumors.

    “Uveal melanoma driver mutations in GNAQ/11 yield numerous changes in melanocyte biology” 
    
Dahlia E. Perez, Andrea M. Henle, Adam Amsterdam, Hannah R. Hagen, Jacqueline A. Lees. Pigment Cell and Melanoma Research. March 2018.

    “Downregulation of TAP1 and TAP2 in early stage breast cancer”

    Andrea M. Henle, Aziza Nassar, Danell Puglisi-Knutson, Bahaaeldin Youssef, Keith L. Knutson. PLOS One. November 2017.

    “The search for novel bacteriophages aboard the International Space Station leads to the identification of two Bacillus species”
    Tristan R Grams, Deborah M. Tobiason, Kasthuri Venkateswaran, Andrea M. Henle. Proceedings of the Wisconsin Space Conference.  August 2017.

    “Enzymatic Discovery of a HER-2/neu Epitope That Generates Cross-Reactive T Cells”

    Andrea M. Henle, Courtney L. Erskine, Linda M. Benson, Raphael Clynes and Keith L. Knutson.  Journal of Immunology.  January 2013.

    “Determining Optimal Cytotoxic Activity of Human Her2neu Specific CD8 T cells by Comparing the Cr51 Release Assay to the xCELLigence System”
    Courtney L. Erskine, Andrea M. Henle, and Keith L. Knutson.  Journal of Visualized Experiments. August 2012.